News and Blogs
News and Blogs
Antiseptic Swabsticks for Optimal Blood Donor Arm Disinfection
2023-08-17
Antiseptic Swabsticks for Optimal Blood Donor Arm Disinfection
Antiseptic Swabsticks for Optimal Blood Donor Arm Disinfection Blood transfusion-associated sepsis resulting from bacterially contaminated blood components remains a major concern for patient safety. The skin of blood donors harbors resident microflora that can lead to contamination if they are introduced into blood collection bags. Effective skin antisepsis at the phlebot...
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Comparing Swab Methods For Vaginal Microbiome Analysis
2023-08-17
Comparing Swab Methods For Vaginal Microbiome Analysis
Comparing Swab Methods For Vaginal Microbiome Analysis Traditionally, 16S rRNA gene sequencing has been considered the gold standard for characterizing the vaginal microbiome using swabs. However, this technique is relatively expensive and time-consuming. Recent studies have evaluated faster and cheaper alternative methods for analyzing vaginal swabs, while maintaining hig...
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Everything You Need To Know About CHG Swabsticks
2023-08-15
Everything You Need To Know About CHG Swabsticks
Everything You Need To Know About CHG Swabsticks What are CHG swabsticks? Chlorhexidine gluconate (CHG) swabsticks are antiseptic wipes used to prepare skin prior to injections, surgical procedures, or access of indwelling medical devices. They contain CHG, an antimicrobial that reduces bacteria on the skin. Why use CHG swabsticks? Using CHG swabsti...
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How to Prevent DNA Degradation in Urine Samples?
2023-08-08
How to Prevent DNA Degradation in Urine Samples?
How to Prevent DNA Degradation in Urine Samples? DNA in urine degrades rapidly, which hinders its application in individual identification. How can we prevent DNA degradation in urine and improve its value in forensics? What substances in urine promote DNA degradation? Urine contains urea, uric acid, creatine, mineral salts, urokinase and other substances tha...
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Systematic Optimization of Urine DNA Isolation for Microbiome Sequencing
2023-08-08
Systematic Optimization of Urine DNA Isolation for Microbiome Sequencing
Systematic Optimization of Urine DNA Isolation for Microbiome Sequencing Recent advances in DNA sequencing technology have enabled the characterization of microbial communities in different parts of the human body using culture-independent techniques. Studies using these methods have demonstrated that the urinary tract contains diverse microbial populations, termed the uri...
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Enhance DNA Extraction from Urine Using Tris-EDTA Treatment
2023-08-08
Enhance DNA Extraction from Urine Using Tris-EDTA Treatment
Enhance DNA Extraction from Urine Using Tris-EDTA Treatment Urine samples are commonly used for molecular detection of bacteria that colonize the genital tract. However, low concentrations of bacteria and the presence of PCR inhibitors like urea and crystals in urine can hamper efficient DNA extraction and subsequent molecular testing. A study in 2019 aimed to develop an o...
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UTI Stops DNA Degradation in Frozen Forensic Urine Samples
2023-08-08
UTI Stops DNA Degradation in Frozen Forensic Urine Samples
UTI Stops DNA Degradation in Frozen Forensic Urine Samples Urine represents an abundant and easily accessible biological material that could provide an alternative source of DNA for forensic genotyping and identification. However, DNA from urinary epithelial cells and cell-free DNA tends to degrade rapidly from enzymatic, chemical, and microbial damage during storage. This...
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How Hydrophobicity Makes THC Tricky to Handle Analytically
2023-08-02
How Hydrophobicity Makes THC Tricky to Handle Analytically
How Hydrophobicity Makes THC Tricky to Handle Analytically Why is THC so Extremely Hydrophobic? THC is highly hydrophobic, with an octanol-water partition coefficient (log Kow) as high as 6.4. This extreme hydrophobicity arises from THC's chemical structure containing effective alkyl substituents and aromatic ring systems. The numerous nonpolar C-H bonds in THC stre...
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Saliva Collector Benefits for Roadside Drug Testing
2023-08-02
Saliva Collector Benefits for Roadside Drug Testing
Saliva Collector Benefits for Roadside Drug Testing Drug testing has advanced significantly in recent years, with increasing use of alternative specimens to blood or urine to detect drug exposure. Oral fluid has emerged as a promising non-invasive specimen for drug testing, particularly to identify recent drug use. Technological developments have also enabled on-site oral ...
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Diagnostic Odysseys: The Critical Role of Viral Transport Media
2023-08-02
Diagnostic Odysseys: The Critical Role of Viral Transport Media
Diagnostic Odysseys: The Critical Role of Viral Transport Media The successful diagnosis of viral infections relies heavily on proper collection, transport, and timely inoculation of clinical specimens containing infectious viral particles. Different viruses exhibit wide variability in composition, structure, morphology, stability and susceptibility to inactivation. Optimi...
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Collecting Poop? You Need Cary-Blair, The Microbiome Saver
2023-07-28
Collecting Poop? You Need Cary-Blair, The Microbiome Saver
Collecting Poop? You Need Cary-Blair, The Microbiome Saver The human gut microbiome plays an important role in health and disease. Advances in sequencing have enabled detailed characterization of the gut microbiota composition. However, sample collection and storage can significantly impact the bacterial composition. This highlights the need to optimize fecal sampling prot...
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The Hidden Truth of Group B Streptococci Survival in Amies Transport Medium
2023-07-28
The Hidden Truth of Group B Streptococci Survival in Amies Transport Medium
The Hidden Truth of Group B Streptococci Survival in Amies Transport Medium Recently, a research team led by Annaliesa S. Anderson from the American pharmaceutical company Pfizer, explored the potential of maternal immunization with an infant Group B Streptococcus vaccine. The findings of this study were published in the New England Journal of Medicine on July 19, 2023. ...
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